Ensuring the optimal temperature for chemical reactions in production processes is critical, and so is the need for a heating/cooling solution. It is essential that Process Engineers are able to strike a balance between yield quality and productivity.
Over the years, Proceca with its team of experts has perfected the art of developing Single Fluid Heating and Cooling Systems for accurate heat transfer for processes. In Active Pharmaceutical Ingredient (API) manufacturing, contrary to the traditional use of multiple utilities, a single fluid heat transfer system is advantageous. These systems can be designed even for specific applications and engineered, built at the client’s site.
APPLICATIONS OF SINGLE FLUID TEMPERATURE CONTROL UNITS
A Single Fluid Heat Transfer System is normally connected to a single reactor and it helps in maintaining a constant temperature difference between the reactor mass and fluid temperature, which provides precise control over heating and cooling rates. Thus, the temperature and the heating-and-cooling time are controlled as critical process parameters resulting in batch-to-batch consistency and a higher yield of the product.
Single Fluid systems can also be used for an entire plant with multiple reactors. In the case of multi-reactor plants, we offer single fluid skids with different header temperatures that are then used in conjunction with reactor automation for temperature control.
A single fluid system is most useful in very high-temperature reactions, as the reactor mass temperature needs to be brought down slowly to room temperature, after the reaction. Gradual cooling is feasible only by maintaining a constant temperature difference between the mass and the jacket, which can be precisely done with our Single Fluid System.
ADVANTAGES OF PROCECA DESIGNED SINGLE FLUID SYSTEMS
- No leakage at the process area (which helps in maintaining cleanliness and hygiene at the plant).
- The operation is corrosion-free.
- No cross-contamination of utilities.
- Centralized Control
- Precise temperature control.
- Easy to Maintain & Easy to Clean
- No thermal shocks to the reactor.
- PLC, HMI Based heating & cooling operations without any supervision of operators.
- Accurate temperature control with +/- 1 °C without any problems with the reactor.
- No hot and cold spots – this results in consistent product yields and quality – a regulatory requirement for APIs
